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#SarsCoV2

38 postitusega20 osalejaga0 postitust täna

People refer to Covid in the past tense because they WANT it to be over… not because it actually IS over.

We’ve all suffered a collective trauma, and most people are refusing to process or deal with it.

A few key points people are determined to “forget”:

“During Covid” is now.

“During the pandemic” is now.

Covid is not over.

Covid IS airborne.

Masks, especially well fitted N95s, offer excellent protection

Anyone can get Long Covid, and your risk increases with each infection.

Even if your initial infection was “mild”, you could have long term damage to your vascular system, immune system, lungs and brain.

Repeat infections are NOT inevitable.

We CAN beat the pandemic together. But it involves collective effort. It involves acknowledging we’re still in a pandemic and “you do you” isn’t working. It involves caring about the air we share, and being willing to adapt.

Let’s make 2025 the year we can actually begin putting Covid in the past!

medRxiv · Dysautonomia in long COVID is prevalent and could explain the frequency of symptomsBackground Long COVID presents with a variety of symptoms. Some of those symptoms could be related to autonomic dysfunction. Our aim is to evaluate the prevalence of autonomic dysfunction in long COVID patients. Methods We conducted a cross-sectional study and included all consecutive patients enrolled in several clinical research studies. We performed the following autonomic dysfunction markers: heart rate variability, heart rate, systolic and diastolic blood pressure changes during NASA lean test, cardiopulmonary exercise testing and a COMPASS-31 scale. We used linear regression to calculate the contribution of each dysautonomia measure on symptom burden as measured by the modified COVID-19 Yorkshire scale. Results We included 100 patients for this study. Our sample had a mean age of 56+/-11 years, included 53% minorities and 32% were women. Dysautonomia as defined by an abnormal COMPASS-31 was seen in 82%; 95% 72-89 while cardiovascular resting dysautonomia as represented by an abnormal heart rate variability was seen in 60%; 95% 48-70 of the population, orthostatic hypotension in 12% and POTS in 10%. In our adjusted analysis, we found that the beta coefficient for the COMPASS-31 score (0.37) was significant on changes in a self-reported long COVID symptom burden. The orthostatic intolerance and gastrointestinal domains of the COMPASS-31 was associated the highest long COVID symptom burden. Conclusion Dysautonomia is common in long COVID patients and contributes to the overall symptoms seen in long COVID. Identifying dysautonomia has important diagnostic and therapeutic implications. ### Competing Interest Statement The authors have declared no competing interest. ### Clinical Trial NA ### Funding Statement Yes ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: All studies were approved by the research ethics committees at the Miami VAHS and NOVA Southeastern University and all participants signed informed consent prior to participation. Miami VA is the IRB of record I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes Data cannot be shared publicly because it is owned but the Veterans Affairs.

New UK research:

Long-term effects of #SARSCoV2 infection on blood vessels and blood pressure

journals.lww.com/jhypertension

"Persistent vascular dysfunction and BP increase post-COVID-19 underscore the need for further studies on the long-term risk of hypertension & cardiovascular disease”

@longcovid
#LongCovid #PwLC #LC #PASC #postcovid
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver

New study shows that COVID may damage your immune system for a year post infection.

This is the problem with ignoring a pandemic in favour of a “you do you” approach.

There’s so much Covid that most people get it at least once per year. Their immune systems don’t have time to recover before they become infected again.

Disability advocates have been screaming about this for years. We beg people to mask up for their own protection and to make public spaces safer and more accessible for us.

We don’t yet know what the long term prognosis will be after 5, 10 or 15+ infections.

Wear a mask. Clean and ventilate the air. Do your part to minimize the spread.

cidrap.umn.edu/covid-19/covid-

CIDRAPCOVID-19 may put patients at risk for other infections for at least 1 year

Origines du covid: l’Académie de médecine accrédite à son tour la thèse de l’accident de laboratoire

Après les services de renseignement américain et allemand, c’est l’Académie nationale de médecine française qui donne du crédit à la thèse de la fuite de laboratoire à l’origine de la pandémie de #SARSCoV2. Mais elle insiste tout autant sur le risque des zoonoses, accru par la destruction de l’environnement.

mediapart.fr/journal/internati

📗 "Viral Modernism: The Influenza Pandemic and Interwar Literature" by Elizabeth Outka

Have you wondered too: why is covid barely visible in modern media? Why do I never pick up a book with someone wearing a mask, even though it's 2020 in the story? Why do I watch tv shows set in 2021 and they act like everything is fine? I have to dig deep for any text that dares to mention the unmentionable (ongoing) SARSCoV2 pandemic, and that really bothers me.

Turns out this is not a rare phenomenon. The same happened after Spanish Flu a full century ago. This book from 2019 digs into the why of it, and then goes on to analyze the presence of the 1918 pandemic in the very few books that did mention it.

The book is divided into three parts. Part 1 zooms in on 'why?'. Why was the flu silenced in literature? Why was it such a taboo? Even if you're not interested in reading the rest of this book, this part is worth it if you've been wondering the same. It has some interesting theories. Partly the war overshadowed the pandemic. But partly it's also a problem of a lack of language and narrative. War is easy to explain: us, the goodies, fight a 'them', the baddies, and someone wins. But a virus is invisible and not well-understood. The 'enemy' doesn't invade from the outside, but spreads throughout your loved ones, penetrates your body and blurs all the lines of who's what. There was a lot of guilt about participation and ignorance. On top of the grief, there's a societal view of sickness as weakness, and of caring and ill health with femininity, which didn't help. I won't recap all of the book here, but it was a fascinating read to see why the pandemic was hidden in media, and how so much can be applied to the current times too. Plus there were lots of archival pictures that I'd never seen before!

In part 2 several books from around that era are discussed and the role of the pandemic in the story is analyzed. I was afraid that it might be too academic for me, but it was quite readable. Most notably I've gotten a more negative view of Virginia Woolf. Although she was one of the few acknowledging sickness in her literature, she also minimized Spanish Flu in daily life, not wanting to engage with it. I was also surprised to see 'look to windward' appear, which I've only known as a quote on war through Bank's books. And wow, the amount of 'living dead' analogies that pop up, interesting stuff.

Part 3 goes into two major trends that became popular post-pandemic: spiritualism and zombie tales. Both are forms of the dead coming back, one for mourning and peace of mind, the other for an outlet for fear and anger. I got quite upset reading about seances where ghosts of flu victims return to earth to exonerate their families from guilt of infection, hmpf. Either way, I thought it was engrossing. In hindsight, it all makes sense, and it helps me understand the way people behave now.

At the end the book states that we're not ready for a new pandemic, although we could be, if only we'd look reality in the eyes and prepare well. Covid started and... here we are. Millions dead, many more millions chronically ill, ableism abound, covid still around and mutating. And probably more pandemics coming at us in the near future. Every day I feel stronger about not letting this truth go unsaid. It's uncomfortable, but more tragedies will occur if the majority of people keep avoiding unpleasant realities. Don't look away, don't underestimate yourself -you can bear it and do your part to keep the people around you safe and well.

As the book says: "Reading the letters and stories told by the survivors of the pandemic —and the literary representations that simultaneously revealed and hid these very stories— launch us into new narrative streams, allowing us to hear voices long ignored in part because the viral, dust-like form at the heart of the story was itself invisible and silent."

I'm adding this book under #PlagueBook and I've also gone back and tagged all previous books that talk about pandemics that I've reviewed with that too (in a tiny effort to not lose these works into silence once again). You can view them all here:

c.im/@reading_recluse/tagged/P

Please stay safe and #WearAMask !

Vastatud lõimes

@DenisCOVIDinfoguy they also cite pubmed.ncbi.nlm.nih.gov/358102

which has this absolute adjective of a hypothesis:

SARS-CoV-2 may bind to ACE2 in order to enter the host brainstem cell and change baroreflex sensitivity

because

The integral parts of the brain renin-angiotensin system, as ACE2 enzyme, are highly expressed in the brainstem, which may also be involved in baroreflex sensitivity, playing an important role in HRV.

which would help explain POTS!!

PubMedPotential autonomic nervous system dysfunction in COVID-19 patients detected by heart rate variability is a sign of SARS-CoV-2 neurotropic features - PubMedIncreasing evidence strongly support that the newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to the development of COVID-19-associated central nervous system (CNS) manifestations. The presence of SARS-CoV-2 viral protein in the brainstem, which includes cardiovas …

UPDATED: #Ontario #SARSCoV2 variants.

Of 128 samples from 3/9 - 3/15:
XEC.*: 28.1% (〰️ 28.9%; ⬇️ 39.1%)
LP.8.1.*: 23.4% (〰️ 24.5%; ⬇️ 26.6%)
MC.10.1.*: 10.9% (⬆️ 5.9%; ⬆️ 4%)
LF.7.*: 7.8% (⬇️ 11.1%; ⬆️ 2.6%)

ratnegative.tumblr.com/ONVaria #COVID19

----------

Of the samples collected in Ontario on these weeks, the prevalence of each of these significant variants/lineages are as follows:

- 3/9 - 3/15 -
• XEC.* (incl. XEC.2, ".5, ".8, ".11.1, ".14, ".16, ".18, ".21): 28.1%
• LP.8.1.* (incl. LP.8.1.1, NY.3, ".7): 23.4%
• MC.10.1.* (incl. MC.10.1.1, ".10.1.6): 10.9%
• KP.3.3.2.* (incl. NP.1): 3.9%
• LF.7.*: (incl. LF.7.7.1, ".7.7.2): 7.8%

- 3/2 - 3/8 -
• XEC.* (incl. XEC.1 - ".3, ".5, ".8, ".10, ".11.*, ".14, ".18, ".21, ".24): 28.9%
• LP.8.1.* (incl. LP.8.1.1, ".8.1.3, NY.1, ".7): 24.5%
• MC.10.1.* (incl. MC.10.1.2, ".10.1.5, ".10.1.6, PA.1): 5.9%
• KP.3.3.2.* (incl. NP.1): 9.1%
• LF.7.*: (incl. LF.7.1.2, ".7.2.1, ".7.7.2, ".7.8): 11.1%

X.X.* in text = X.X & descendants.

X.X.* in graph = all descendants of X.X, except for ones with own segment of week’s bar.

I just had a guy get angry at me for saying we’re still in a pandemic. He said it was fear mongering and “silly” to continue to take precautions.

He then went on to say his wife has Long Covid and he’s had Covid “at least 4-5 times”.

This attitude is why we’re in this mess. His own wife was disabled by Covid, and rather than adapt his behaviour he’s exposed her 4-5 additional times.

Repeat infections are devastating to those with Long Covid. Not to mention each infection does cumulative damage, and eventually you will be left disabled.

Even if you’re someone who believes it’s “just a flu”… surely you recognize people didn’t get the flu 4-5 times in a four year period? Being sick that often is an aberration, and a darn good reason to take precautions.

You know who hasn’t had COVID 4-5 times? People who are taking precautions.

Bonus tip: If you’re masking and you become infected anyways, you’ve reduced your viral load AND you’ve made sure not to infect anyone else. That’s community care & compassion and it’s worth doing.

Vastatud lõimes

@Cyclad @alleburgers

De Washington Post benadrukt dat elke infectie leidt tot vermindering van de hersenfunctie. Na #Covid ervaren mensen #Brainfog, doen het minder goed op cognitieve taken, en verandert de hersenstructuur zichtbaar hersenscans.

Twee meta-analyses (onderzoek waarin andere onderzoeken worden gecombineerd) laten zien dat elke infectie met #SARSCov2 het risico op #Dementie verhoogt.

locovid.nl/oversterfte-ziekte-

#LongCovid @LongcovidNieuws

locovid.nlOversterfte, ziekte en verspreiding Covid19 2025-12 – Low Covid info & actie

UPDATED: #Ontario #SARSCoV2 variants.

Of 50 samples from 3/2 - 3/8:
XEC.*: 22% (⬇️ 37.6%)
LP.8.1.*: 20% (⬇️ 30.1%)
KP.3.3.2.* (incl. NP.1): 20% (⬆️ 5.8%)
LF.7.7.2: 24% (⬆️ 3.5%)

ratnegative.tumblr.com/ONVaria #COVID19

-----------

Of the samples collected in Ontario on these weeks, the prevalence of each of these significant variants/lineages are as follows:

- 3/2 - 3/8 -
• XEC.*: 22%
• JN.1.11.1.*: 48%
→ LP.8.1.* (incl. LP.8.1.1): 20%
→ KP.3.* (only KP.3.1.1.*, ".3.3.2.*): 28%
→ KP.3.1.1.* (incl. MC.1.2, ".21.1): 8%
→ KP.3.3.2.* (incl. NP.1): 20%
→ NP.1: 4%
• JN.1.16.1.* (incl. LF.7.2.1, ".7.7.2): 28%
→ LF.7.7.2: 24%

- 2/23 - 3/1 -
• XEC.*: 37.6%
• JN.1.11.1.*: 49.7%
→ LP.8.1.* (incl. LP.8.1.1.*): 30.1%
→ KP.3.* (only KP.3.1.1.*, NP.1 ctd.) †: 19.7%
→ KP.3.1.1.* (incl. MC.1.*, ".10.*, ".13.*, ".24, ".31): 13.9%
→ MC.1.* (incl. MC.1.2, ".1.6, ".1.7): 6.9%
→ KP.3.3.2.* (only NP.1 ctd.): 5.8%
• JN.1.16.1.* (incl. LF.7.2.1, ".7.7.*): 5.8%
→ LF.7.7.2: 3.5%

† 1 KP.3.3.2 & 1 KP.3.3.5 sample ctd. as JN.1.*

X.X.* in text = X.X & descendants.

X.X.* in graph = all descendants of X.X, except for ones with own segment of week’s bar.

Mask bans are ableist, discriminatory ugly laws.

Disabled advocates have been warning for years that if people didn’t help normalize masking, bans would follow

Please call legislators in New York and tell them No mask bans!

Medical exemptions aren’t enough, everyone needs the legal right to mask

The police are not doctors. They can’t determine who’s “sick enough” to wear a mask.

Many people with invisible illnesses struggle to get healthcare workers to take us seriously. We don’t want to be questioned by police.

Everyone should be allowed to mask up to prevent covid.

Vastatud lõimes

Some highlights from @ducky 's weekly roundup at covidbc.webfoot.com/2025/03/28

SARS-CoV-2 can interact with / activate the CD147 receptor to get into lymphocytes (T-cells and B-cells). (sciencedirect.com/science/arti)

women are 13.4 times more likely to get Long COVID if they are 🤰pregnant than if they are 🚫🤰not, with the danger highest if they catch COVID-19 in the third trimester. (sciencedirect.com/science/arti)

the rate of cases of postural orthostatic tachycardia syndrome (POTS) has gone up more than fourteen times compared to pre-pandemic (academic.oup.com/ehjqcco/advan)

covidbc.webfoot.com2025-03-28 General – Pandemics in British Columbia

Over 5 years since officially recognised records of #SARSCoV2 infections in the UK - the virus that causes the disease known as COVID-19.
@ukhsa.bsky.social data provide a stark reminder of the impact of the disease.
Yet, still, there is a reticence to accept that the virus is an airborne pathogen.