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est.social on üks paljudest sõltumatutest Mastodoni serveritest, mida saab fediversumis osalemiseks kasutada.
est.social on mõeldud Eestis üldkasutatavaks Mastodoni serveriks. est.social is meant to be a general use Mastodon server for Estonia.

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#physiology

5 postitusega5 osalejaga1 postitust täna
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JuneSim63

Interesting new study on physiological links to social isolation:

"We investigated the association between proteins and self-reported loneliness and social isolation. We discovered that the proteins found to be significantly associated with loneliness and social isolation are also known to be implicated in inflammation as well as antiviral and immune responses"

#Loneliness #SocialIsolation #Proteins #Physiology #Immunology #Science

theconversation.com/loneliness

The ConversationLoneliness and social isolation are linked to specific proteins – new researchPeople who feel lonely tend to have higher levels of five key proteins.
Avalik
SPQR

We conclude that healthy older adults show evidence of mitochondrial impairment and muscle weakness, but that this can be partially reversed at the phenotypic level, and substantially reversed at the transcriptome level, following six months of resistance exercise training.
#science #aging #exercise #physiology #biology #pathology #muscles #training #health
journals.plos.org/plosone/arti

journals.plos.orgResistance Exercise Reverses Aging in Human Skeletal MuscleHuman aging is associated with skeletal muscle atrophy and functional impairment (sarcopenia). Multiple lines of evidence suggest that mitochondrial dysfunction is a major contributor to sarcopenia. We evaluated whether healthy aging was associated with a transcriptional profile reflecting mitochondrial impairment and whether resistance exercise could reverse this signature to that approximating a younger physiological age. Skeletal muscle biopsies from healthy older (N = 25) and younger (N = 26) adult men and women were compared using gene expression profiling, and a subset of these were related to measurements of muscle strength. 14 of the older adults had muscle samples taken before and after a six-month resistance exercise-training program. Before exercise training, older adults were 59% weaker than younger, but after six months of training in older adults, strength improved significantly (P<0.001) such that they were only 38% lower than young adults. As a consequence of age, we found 596 genes differentially expressed using a false discovery rate cut-off of 5%. Prior to the exercise training, the transcriptome profile showed a dramatic enrichment of genes associated with mitochondrial function with age. However, following exercise training the transcriptional signature of aging was markedly reversed back to that of younger levels for most genes that were affected by both age and exercise. We conclude that healthy older adults show evidence of mitochondrial impairment and muscle weakness, but that this can be partially reversed at the phenotypic level, and substantially reversed at the transcriptome level, following six months of resistance exercise training.
Avalik
SPQR

This memory arises because the experience of obesity leads to changes in the epigenome — a set of chemical tags that can be added to or removed from cells’ DNA and proteins that help to dial gene activity up or down. For fat cells, the shift in gene activity seems to render them incapable of their normal function.
#nutrition #genetics #obesity #physiology #epigenetics #science nature.com/articles/d41586-024

www.nature.comFat cells have a ‘memory’ of obesity — hinting at why it’s hard to keep weight offLong-lasting changes to the cells’ epigenome are linked to a decline in their function.
Avalik
Rhyothemis

OMG - I did not know this -

Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response
doi.org/10.1016/j.cell.2008.02

I have not yet read the article, nor have I finished watching the video that had me look up the article:

Tissue identity and rejuvenation - going skin deep with Luis Garza!
youtu.be/5iEXYrnZsuM?si=1v2t19

I had to stop everything and post about this since I'm gobsmacked.

How did I not know this?
The implications for chronic illnesses could be huge.

I need to get back to my chores now, I will probably post more on this later.

#biology #medicine
#physiology #OxygenSensing
#hypoxia #dermatology #HBOT

Vastatud lõimes
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Preston MacDougall

@ChemistryViews The genesis of #AI was the PhD advisor of #GeoffreyHinton , Christopher Longuet-Higgins who relocated to #Edinburgh from the #Chemistry Department at Cambridge to focus his research on modelling how the brain 🧠 processed information using what was then known about the #chemistry and #physiology of neurons. 👉 inf.ed.ac.uk/events/christophe

www.inf.ed.ac.ukSchool of Informatics: in memoriam Hugh Christopher Longuet-Higgins
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Avalik
Preston MacDougall

@Mopsi The genesis of Longuet-Higgins research was to model the way the brain 🧠 processed information using what was known about the #chemistry and #physiology of neurons. 👉 inf.ed.ac.uk/events/christophe

But you’re right, #physics is a stretch for Hinton. Hopfield is well-known in Theoretical Physics (electron transport), so that may be why the Physics Committee claimed #AI with this #NobelPrize. 🤔

www.inf.ed.ac.ukSchool of Informatics: in memoriam Hugh Christopher Longuet-Higgins
Avalik *
Sophia Bullock

#Introduction
So here I am, someone who tried and failed Twitter numerous times, now attempting to get a handle on this 😂 I don't know if I'm on the right server, I guess time will tell!

I'm a #PhDStudent at #NewcastleUniversity using #animalBehaviour, #neuroscience, #physiology and #socialScience to improve #laboratory #animalWelfare (jeez that's a lotta hashtags!). 🐀

In my spare time I enjoy hunting, identifying, and sometimes even eating #fungi. I also like #photography and #baking vegan goodies 🍰

Image of a rock formation on a rocky beach with the sea and cliffs in the background. The sky is blue with some white fluffy clouds.
Avalik
Project Gutenberg

German physicist and physician Hermann von Helmholtz was born #OTD in 1821.

His 1847 work, Über die Erhaltung der Kraft, articulated the idea that energy cannot be created or destroyed, only transformed from one form to another. In physiology, he invented the ophthalmoscope in 1851. His book On the Sensations of Tone as a Physiological Basis for the Theory of Music (1863) explored the physical basis of musical harmony and the physiology of hearing.

en.wikipedia.org/wiki/Hermann_

Helmholtz in 1881, portrait by Ludwig Knaus. In this portrait, Helmholtz is portrayed as a man in his early sixties, with a strong, thoughtful expression. His face is characterized by sharp, defined features, including a high forehead, prominent nose, and a well-groomed mustache and beard that were typical of his era. His hair is gray, thinning slightly, but still full, adding to his distinguished appearance. Helmholtz is dressed in formal attire, wearing a dark suit with a white shirt and a bow tie, which reflects his professional standing and the seriousness with which he approached his scientific work. The clothing is meticulously detailed, with the texture of the fabric and the folds of the suit rendered with precision, showcasing Knaus's skill as a portraitist.
#physics#physiology
Avalik
Project Gutenberg

Medical doctor Ronald Ross was born #OTD in 1857.

In 1897, Ross made a significant breakthrough when he discovered that malaria parasites were transmitted by mosquitoes. He found malaria parasites in the stomach tissue of a mosquito and demonstrated their life cycle in the insect. He was awarded the Nobel Prize in Physiology or Medicine in 1902, becoming the first British Nobel laureate in Medicine.

Books by Ronald Ross at PG:
gutenberg.org/ebooks/author/44

Ronald Ross, winner of Nobel Prize in Medicine
The page in Ross' notebook where he recorded the "pigmented bodies" in mosquitoes that he later identified as malaria parasites.
#books#physiology#medicine
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Teave